Drug-acceptor interactions modeling theoretical tools to test and evaluate experimental equilibrium effects
Drug-Acceptor Interactions: Modeling theoretical tools to test and evaluate experimental equilibrium effects suggests novel theoretical tools to test and evaluate drug interactions seen with combinatorial drug therapy. The book provides an in-depth, yet controversial, exploration of existing tools f...
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| Formato: | Libro electrónico |
| Idioma: | Inglés |
| Publicado: |
[Place of publication not identified] :
Taylor & Francis
2008.
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| Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009745296206719 |
Tabla de Contenidos:
- Part I ONE-STATE MODELS: SIMPLE AGONISM AND ANT-AGONISM
- CHAPTER 1 Simple agonism
- CHAPTER 2 Simple ant-agonism simple intervention
- CHAPTER 3 Auto-inhibition and auto-intervention in one-state models
- CHAPTER 4 Means of obtaining ant-agonist constants: Preliminary points of a personal view
- Part II TWO-STATE MODELS: COMPLEX AGONISM AND MODULATION
- CHAPTER 5 Complex agonism
- CHAPTER 6 Multi-step reaction schemes: extending the two-step mechanism of del Castillo and Katz
- CHAPTER 7 Cubic reaction schemes. ATSM and HOTSM
- Part III TEST OF TOOLS FOR DATA ANALYSIS
- CHAPTER 8 Choosing and formulating relevant schemes
- CHAPTER 9 Plots, fits and data interpretation.
- CHAPTER 10 Hill in hell
- CHAPTER 11 The Schild against other theories
- CHAPTER 12 Ties between synergy and two-state models
- Part IV BIOLOGICAL REGULATION AND ALLOSTERY
- CHAPTER 13 Strategies of biological regulation
- CHAPTER 14 On allostery and co-operativity
- CHAPTER 15 Allostery and development of its models.
