O-GlcNAcylation and cancer
his book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcription...
| Otros Autores: | , |
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| Formato: | Libro electrónico |
| Idioma: | Inglés |
| Publicado: |
Basel :
MDPI - Multidisciplinary Digital Publishing Institute
[2022]
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| Materias: | |
| Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009745152106719 |
Tabla de Contenidos:
- 1. Introduction
- 2. O-GlcNAcylation
- 2.2. Functions of O-GlcNAcylation
- 3. O-GlcNAcylation and Cancer
- 3.1. O-GlcNAcylation and Metastasis
- 3.2. O-GlcNAcylation and Receptor Tyrosine Kinase
- 3.3. O-GlcNAcylation and Resistance to Chemotherapy
- 3.4. O-GlcNAcylation as Prognostic Marker
- 4. O-GlcNAcylation and Immune Responses in Cancer
- 4.1. Overview of Immune System and O-GlcNAcylation
- 4.2. T Cell Activation and Differentiation Regulated by O-GlcNAcylation
- 4.3. Macrophage Differentiation and Activation by O-GlcNAcylation
- 4.4. O-GlcNAcylation and Tumor Microenvironment
- 5. Cancer Therapeutics Targeting O-GlcNAcylation
- 6. Conclusions and Future Perspectives
- Author Contributions
- Funding
- Conflicts of Interest
- Footnotes
- References.
