Genetic testing : a survey of quality assurance and proficiency standards

Genetic testing a survey of quality assurance and proficiency standards

This report presents the results of a survey of over 800 genetic testing laboratory directors in 18 OECD countries. It provides the first detailed overview of the availability and extent of molecular genetic testing across OECD member countries. The survey allowed the OECD to compare practices in in...

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Detalles Bibliográficos
Autor principal: Organisation for Economic Co-operation and Development.
Autor Corporativo: Organisation for Economic Co-operation and Development (-)
Formato: Libro electrónico
Idioma:Inglés
Publicado: Paris : OECD c2007.
Materias:
Human chromosome abnormalities > Diagnosis > Standards.
Laboratories > Standards.
Scientific surveys > OECD countries.
Human chromosome abnormalities > Diagnosis > International cooperation.
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009705383006719
Tabla de Contenidos:
  • Foreword; TABLE OF CONTENTS -; Summary; Introduction; Study population; Growth, configuration and organisation of genetic testing services; Close collaboration between clinical and laboratory services; Technology; Referral systems and gatekeeping arrangements; Funding and uptake of genetic tests; Geographical disparity in the range of genetic tests available; The growth of genetic testing networks; Handling of samples and data; Risk management; Determinants of laboratory personnel competence; References; Résumé; Introduction; Composition de l'échantillon
  • Essor, configuration et organisation des services de test génétiqueCollaboration étroite entre services cliniques et laboratoires; Technologie; Systèmes de référents et mécanismes d'aiguillage/filtrage; Financement et utilisation effective des tests génétiques; Disparités géographiques dans la gamme des tests disponibles; L'essor des réseaux sur les tests génétiques; Manipulation des échantillons et des données; Gestion des risques; Facteurs déterminant la compétence du personnel des laboratoires; Références
  • Chapter 1. Quality Assurance in Molecular Genetic Testing: Results of a Survey of 18 CountriesIntroduction; Methods; Steering committee; Study population; Survey development; Validation of the survey instrument; Contact of potential laboratory directors; Prevention of duplicate entries; Calculation of result reporting and QA best practice indices; Statistical analysis; Results; Study population; Laboratory setting; Personnel qualifications; Specimens; Types of testing being offered; Number of specimens accessioned; Methods used; Reporting practices; Informed consent and confidentiality
  • Licensing and proficiency testing participationPatented tests; Quality assurance practices of the laboratories; Chapter 2. Transborder Flow and Rare Diseases; Introduction; Background information; Summary of survey results; Dimension of transborder flow; Countries receiving samples; Current practice; Bivariate analysis of the transborder flow; Multivariate analysis of the transborder flow; Discussion; Dimension of transborder flow; Regulatory environment; Current practice; Conclusions; Improving availability of rare-disease testing; Promoting quality testing
  • Improving access to rare-disease testingChapter 3. Report Writing; Introduction; The reporting quality score; Survey results: analysis and discussion; Respondents not issuing reports; Range of scores; Factors influencing reporting quality score; Conclusions; References; Chapter 4. Consent, Storage and Confidentiality; Introduction: critical issues; Storage; Confidentiality; Informed consent; Survey results, analysis and discussion; Laboratory setting; Confidentiality; Conclusions; References
  • Chapter 5. Licensing, Accreditation, Certification and Proficiency Testing/External Quality Assessment

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