Xenotransplantation International Policy Issues
Over one million people world-wide have benefited from successful tissue and organ transplants and survival rates have dramatically improved. But transplantation has become a victim of its own success. The demand for human organs can no longer be met and deaths of persons on waiting lists have more...
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| Formato: | Libro electrónico |
| Idioma: | Inglés |
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Paris :
OECD Publishing
1999.
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| Colección: | Proceedings
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| Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009704855106719 |
Tabla de Contenidos:
- SUMMARY OF POLICY CONSIDERATIONS FROM THE NY’98 WORKSHOP
- Part I. Transplantation
- 1. INTERNATIONAL TRANSPLANTATION ISSUES: PROBLEMS AND NEEDS
- The core of the problem: the shortage of organ donors
- Can the organ procurement gap be narrowed?
- 2. IMMUNOLOGICAL HURDLES FOR TRANSPLANTATION
- Current methods to prevent rejection
- New immunosuppressive drugs
- Infections in organ transplant recipients on immunosuppressive treatment
- 3. NEW APPROACHES TO INDUCE TOLERANCE
- Inbred miniature swine and cloning
- Part II. Xenotransplantation
- 1. A HISTORICAL PERSPECTIVE
- 2. PIGS AS ORGAN DONORS
- Science: perspectives and issues
- Will pig organs be physiologically capable of supporting prolonged human life
- Infectious risk: What precautions should be taken to avoid the transfer of porcine pathogens?
- Micro-organisms that pigs may harbour
- 3. BABOONS AS ORGAN DONORS
- What is the risk of infectious disease when performing baboon-to-man transplants
- Part III. International Policy Issues in Xenotransplantation
- 1. HANDLING THE RISK: THE CHALLENGE OF INTERNATIONAL SURVEILLANCE
- Notification systems
- Registry systems
- Archive systems
- 2. INTERNATIONAL CO-OPERATION
- Current developments on national and international draft guidelines on xenotransplantation
- 3. LESSONS LEARNED IN GENE THERAPY
- 4. INDUSTRY INVOLVEMENT
- 5. ECONOMIC ASPECTS
- 6. SOCIO-LEGAL AND ETHICAL ASPECTS
- Legal issues
- Ethical issues
- Animal welfare and husbandry
- Public perception
- Developing countries
- Patient monitoring
- CONCLUDING CONSIDERATIONS
- -What is the actual economic burden to society of diseases where xenotransplantation may have a role?
- What are the options today to alleviate organ shortage?
- What are the options today to alleviate the burden of disease where xenotransplantation may have a role?
- What are the options for treatment derived from recent technological advances?
- What public health tools are there to reduce or eliminate the risk of transmission of infectious agents?
- What are the key features of an international framework to detect, identify, monitor, evaluate and manage xenozoonotic risk
- What can we learn from the international regulatory experience on gene therapy?
- How can the OECD and other international organisations assist the development of international public health tools?
- What can we learn about animal welfare and about accessibility, equity and acceptance in the context of xenotransplantation?
- What are the salient features that prevent the adoption of xenotransplantation?
- What are the research gaps that must be addressed to move the field forward?
- Annex I Working Party on Xenografts (of The Nuffield Council on Bioethics): Summary of Recommendations
- Annex II Article 152 of the Amsterdam Treaty (ex Article 129)
- Annex III Recommendation of the Council of Europe
- Annex IV Workshop on Transplantations, Including Xenotransplantations: Proposed Strategy for Developing Research into and Accessibility to these Technologies in Africa and the Third World
- Annex V Joint OECD-New York Academy of Sciences Workshop Programme
- Annex VI Steering and Expert Group for the Preparation of the OECD Workshop New York ‘98
- References
