Test No. 319A : Determination of in vitro intrinsic clearance using cryopreserved rainbow trout hepatocytes (RT-HEP)

Test No. 319A Determination of in vitro intrinsic clearance using cryopreserved rainbow trout hepatocytes (RT-HEP)

The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP suspens...

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Detalles Bibliográficos
Autor principal: Organisation for Economic Co-operation and Development (author)
Autor Corporativo: Organisation for Economic Co-operation and Development, author, issuing body (author)
Formato: Libro electrónico
Idioma:Inglés
Publicado: Paris, France : Organisation for Economic Co-operation and Development Publishing 2018.
Colección:OECD Guidelines for the Testing of Chemicals, Section 3, Environmental fate and behaviour
Materias:
Chemical tests and reagents.
Environment.
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009704658706719

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