Guidelines for diagnosing, preventing and managing cryptococcal disease among adults, adolescents and children living with HIV

Guidelines for diagnosing, preventing and managing cryptococcal disease among adults, adolescents and children living with HIV

Cryptococcal disease is an opportunistic infection that occurs primarily among people with advanced HIV disease and is an important cause of morbidity and mortality in this group. By far the most common presentation of cryptococcal disease is cryptococcal meningitis, which accounts for an estimated...

Full description

Bibliographic Details
Main Author: World Health Organization (author)
Corporate Author: World Health Organization, author, issuing body (author)
Format: eBook
Language:Inglés
Published: Geneva : World Health Organization 2022.
Edition:1st ed
Subjects:
HIV Infections > complications.
See on Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009692738806719
Table of Contents:
  • Intro
  • Definition of key terms
  • Acknowledgements
  • Executive summary
  • 1. Background
  • 1.1 Objectives and target audience
  • 1.2 Guiding principles
  • 2.  RECOMMENDATIONS ON DIAGNOSING AND PREVENTING CRYPTOCOCCAL DISEASE
  • 2.1 Diagnosing cryptococcal disease
  • 2.1.1 Background
  • 2.1.2 Rationale for the recommendations
  • 2.2 Preventing and screening for cryptococcal disease
  • 2.2.1 Background
  • 2.2.2 Rationale for the recommendations
  • 2.2.3 Recommendations for children
  • 3.  RECOMMENDATIONS ON INDUCTION, CONSOLIDATION AND MAINTENANCE ANTIFUNGAL TREATMENT REGIMENS
  • 3.1 Background
  • 3.2 Induction therapy
  • 3.2.1 Rationale for the recommendations
  • 3.3 Preventing, monitoring and managing amphotericin B deoxycholate toxicity
  • 3.4 Drug interactions
  • 3.5 Consolidation and maintenance treatment
  • 3.5.1 Rationale for the recommendations
  • 3.7 Treatment for pregnant women
  • 3.8 Adjunctive corticosteroids in treating HIV-associated cryptococcal meningitis
  • 3.9 Timing of ART initiation
  • 3.9.1 Rationale for the recommendation
  • 3.9.2 Implementation considerations
  • 3.10 Monitoring and managing people with cryptococcal meningitis
  • 3.10.1 Raised intracranial pressure
  • 3.10.2 Cryptococcal immune reconstitution inflammatory syndrome
  • 4.  IMPLEMENTATION CONSIDERATIONS
  • 5.  RESEARCH NEEDS
  • 6. UPDATING AND DISSEMINATION
  • References
  • ANNEX 1. Process for developing the guidelines
  • References
  • Web Annex 1. Declarations of interest for the Guideline Development Group and External Peer Review Group
  • Web Annex 2. Systematic review and GRADE evidence profile on treatment strategies for HIV-associated cryptococcal meningitis
  • Abstract
  • Background
  • Methods
  • Results
  • Discussion
  • Acknowledgements
  • Fig. A1. Study selection
  • Supplemental Fig. 1. Risk of bias summary.
  • Appendix. Search strategy: utility and impact review
  • GRADE evidence profile on updated systematic review of HIV-associated cryptococcal meningitis treatment strategies
  • References
  • Web Annex 3. Evidence-to-decision-making table
  • Summary of judgements
  • Detailed evidence-to-decision-making table.

Similar Items