Marine Drug Research in China: Selected Papers from the 15-NASMD Conference

The Book covers this whole field, from the discovery of structurally new and bioactive natural products (including biomacromolecules), from marine macro-/micro-organisms, to the pharmacodynamics, pharmacokinetics, metabolisms, and mechanisms of marine-derived lead compounds, both in vitro and in viv...

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Detalles Bibliográficos
Otros Autores:	Zhou, Xuefeng (Editor), Luo, Xiaowei (Otro), Liu, Yonghong
Formato:	Libro electrónico
Idioma:	Inglés
Publicado:	Basel MDPI Books 2022
Materias:	Medicine Antarctic krill (Euphausia superba) peptide antioxidant activity stability oyster plasma peptidome antimicrobial peptides cytotoxicity actinomycete piericidins absolute configuration Pestalotiopsis heterocornis heterocornols anti-inflammatory activity sponge-derived fungus sclerotides lipodepsipeptide Aspergillus sclerotiorum nasopharyngeal carcinoma AChE inhibitory vascular endothelial cell flavonoid oxidized low-density lipoprotein Nrf2 apoptosis butyrolactone I food allergy metabolism pharmacokinetics actinomycin X2 microbial pigments dyeing silk antibacterial properties PD-L1 virtual screening pharmacophore modeling ADME molecular dynamics xanthones ascidian-derived fungus Diaporthe sp. anti-glioma activity antiaging Sonneratia apetala signaling pathway Caenorhabditis elegans mutants coral-derived fungi Aspergillus hiratsukae meroterpenoids antibacterial activity cytotoxic activity deep-sea-derived fungus Aspergillus puniceus isoquinoline alkaloid protein tyrosine phosphatase inhibitor antibacterial Aspergillus sp. geodin semisynthesize insecticidal activity Arca inflata antitumor peptide MAPK signaling calmodulin colorectal cancer methicillin-resistant Staphylococcus aureus actinomycin D Streptomyces parvulus mechanism mangrove endophytic Pestalotiopsis Sdy-1 antitumor activity Wnt signaling β-catenin eremophilane sesquiterpenoids mangrove-derived fungus Penicillium sp. Oceanapia sponge secondary metabolites biological activities drug design anticancer cyclic pentapeptide galaxamide analogues skipjack tuna (Katsuwonus pelamis) muscle angiotensin-I-converting enzyme (ACE) peptide molecular docking nitric oxide (NO) endothelin-1 (ET-1) Trichoderma longibrachiatum sesquiterpene glycoside antimicrobial activity marine fungi Aspergillus unguis depsides depsidones osteoclast differentiation soft-coral-derived fungus pyranodipyran derivatives tyrosyl DNA phosphodiesterase 1 inhibitory activities fluorescent properties butenolides enantiomers Aspergillus terreus pancreatic lipase NAFLD fucoxanthin adenosine monophosphate-activated protein kinase (AMPK) nuclear factor erythroid-2-related factor 2-mediated (Nrf2) Toll-like receptor 4-mediated (TLR4) Aspergillus flavipes HN4-13 emodin macroporous resin XAD-16 adsorption kinetics and isotherms enrichment tetramic acid derivatives deep-sea fungus clavipitacae Lecanicillium fusisporum chronic kidney disease fucoidan cognitive dysfunction neuroinflammation oxidative stress GSK3β-Nrf2-HO-1 signaling microglial polarization deep-sea actinomycetes aromatic acids oximes antihyperlipidemic phycocyanin microbiota transcriptome IL-17 pathway Hahella prodiginine chejuenlide genome mining LC-MS/MS CDK4/6 marine compounds pharmacophore construction ADMET mm-pbsa
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