Oncologic Thermoradiotherapy: Need for Evidence, Harmonisation, and Innovation

The road of acceptance of oncologic thermotherapy/hyperthermia as a synergistic modality in combination with standard oncologic therapies is still bumpy. This is partially due to the lack of level I evidence from international, multicentric, randomized clinical trials including large patient numbers...

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Bibliographic Details
Other Authors:	Bodis, Stephan (Editor), Ghadjar, Pirus (Other), Van Rhoon, Gerard C.
Format:	eBook
Language:	Inglés
Published:	Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:	Medicine Oncology perfusion estimation temperature monitoring conductivity reconstruction systems medicine immune system in silico perceptron antigen pattern danger signal fractionation immune response head and neck cancer hyperthermia reirradiation treatment outcome hyperthermia treatment planning adaptive planning temperature optimization low-middle-income group countries cancer radiotherapy chemotherapy recurrent breast cancers cervical cancer head and neck cancers cost-effective meta-analysis intensity-modulated radiotherapy prostate cancer thermal dose thermometric parameters preclinical data clinical evidence modulated electro-hyperthermia abscopal effect locally advanced cervical cancer resource-constrained setting radiosensitiser rectal cancer chemoradiotherapy tumour control loco-regional hyperthermia oncology cellular selection bioelectromagnetics complexity immune-effects moderate hyperthermia deep hyperthermia radiative hyperthermia patterns of care reimbursement regional hyperthermia neoadjuvant chemoradiation survival induced brachytherapy prostatic neoplasms interstitial hyperthermia treatment plan optimization prostate thermoradiotherapy linear quadratic model biological modeling thermal dosimetry hypoxia radiation therapy reoxygenation perfusion oxygen consumption rate local tumor control biomarker immune phenotype hyperthermia treatment sequence breast cancer immune checkpoint molecules dendritic cell activation
See on Biblioteca Universitat Ramon Llull:	https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009669516406719