Shargel and Yu's applied biopharmaceutics and pharmacokinetics

Shargel and Yu's applied biopharmaceutics and pharmacokinetics

"The eighth edition represents the collective contribution of experts with intimate knowledge and experience in the selected subject areas. Each chapter was written to include practical applications of the theoretical material. Frequently asked questions are included to provide a discussion of...

Descripción completa

Detalles Bibliográficos
Otros Autores: Shargel, Leon, editor (editor), Ducharme, Murray P., editor
Formato: Libro electrónico
Idioma:Inglés
Publicado: New York : McGraw-Hill 2022.
Edición:Eighth edition
Materias:
Drugs > Administration.
Biopharmaceutics.
Pharmacokinetics.
Drug Development.
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009666840006719
Tabla de Contenidos:
  • Part I: Introduction to Biopharmaceutics and Pharmacokinetics
  • Chapter 1: Introduction to Biopharmaceutics and Pharmacokinetics
  • Chapter 2: Mathematical Fundamentals in Pharmacokinetics
  • Chapter 3: Biostatistics
  • Part II: Fundamentals of Biopharmaceutics
  • Chapter 4: Physiologic Factors Related to Drug Absorption
  • Chapter 5: Drug Distribution and Protein Binding
  • Chapter 6: Physiology of Drug Elimination
  • Chapter 7: Biopharmaceutic Considerations in Drug Product Design and In Vitro Drug Product Performance
  • Chapter 8: Drug Product Performance, In Vivo: Bioavailability and Bioequivalence
  • Chapter 9: Modified-Release Drug Products and Drug Devices
  • Chapter 10: Targeted Drug Delivery Systems and Biotechnology Products
  • Part III: Pharmacokinetic Principles
  • Chapter 11: Introduction to Pharmacokinetic and Pharmacodynamic Models and Analyses
  • Chapter 12: One-Compartment Open Model: Intravenous Bolus Administration
  • Chapter 13: Multicompartment Models: Intravenous Bolus Administration
  • Chapter 14: Intravenous Infusion
  • Chapter 15: Pharmacokinetic Calculations for Drug Elimination and Clearance
  • Chapter 16: Pharmacokinetics of Drug Absorption
  • Chapter 17: Multiple-Dosage Regimens
  • Chapter 18: Nonlinear Pharmacokinetics
  • Chapter 19: Empirical Models, Mechanistic Models, Statistical Moments, and Noncompartmental PK/PD Analyses
  • Chapter 20: Applications of Software Packages in Pharmacokinetics
  • Part IV: Pharmacodynamics and Clinical Pharmacokinetics
  • Chapter 21: Pharmacogenetics, Drug Metabolism, Transporters, and Individualization of Drug Therapy
  • Chapter 22: Relationship between Pharmacokinetics and Pharmacodynamics
  • Chapter 23: Application of Pharmacokinetics to Clinical Situations
  • Chapter 24: Application of Pharmacokinetics and Pharmacodynamics to Aging, Obese, and Pediatric Patients
  • Chapter 25: Dose Adjustment in Renal and Hepatic Diseases
  • Part V: Biopharmaceutics and Pharmacokinetics in Drug Product Development
  • Chapter 26: Biopharmaceutical Aspects of the Active Pharmaceutical Ingredient and Pharmaceutical Equivalence
  • Chapter 27: Rational Drug Product Development, Quality, and Performance
  • Chapter 28: FDA-Approved Novel Dosage Forms
  • Chapter 29: Clinical Development and Therapeutic Equivalence of Generic Drugs and Biosimilar Products
  • Chapter 30: Pharmacokinetics and Pharmacodynamics in Clinical Drug Product Development
  • Glossary.

Ejemplares similares