Practical instrumental analysis methods, quality assurance and laboratory management
This practical book in instrumental analytics conveys an overview of important methods of analysis and enables the reader to realistically learn the (principally technology-independent) working techniques the analytical chemist uses to develop methods and conduct validation.What is to be conveyed t...
| Autor principal: | |
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| Formato: | Libro electrónico |
| Idioma: | Inglés |
| Publicado: |
Weinheim :
Wiley-VCH
2012.
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| Materias: | |
| Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009665122606719 |
Tabla de Contenidos:
- Title page; Copyright page; Contents; Preface to the German Edition; Preface to the English Edition; Dedication; Foreword; 1: Introduction; 1.1 Analytical Chemistry - The History; 1.2 Analytical Chemistry and Its Role in Today's Society; 2: Introduction to Quality Management; 2.1 Historical Background; 2.2 Variability; 2.3 The Four Pillars of Wisdom (from Shewhart to Deming); 2.4 Zero-Defect Tolerance; 2.5 Why Standards?; 2.6 The Controlled Process; 2.7 ISO Guidelines 9004; 2.8 Quality Management System (QMS) Requirements; 3: Fundamentals of Statistics; 3.1 Basic Concepts
- 3.1.1 Population and Sample3.1.2 Distribution of Values; 3.2 Important Terms; 3.2.1 Mean, Arithmetic Mean, Average (); 3.2.2 Standard Deviation (σ, s); 3.2.3 Variance (Var,V); 3.2.4 Standard Deviation of Mean Values (); 3.2.5 Relative Standard Deviation (RSD) and Coefficient of Variation (CV); 3.2.6 Confidence Interval (CI), Confidence Limits; 3.3 Quality of Results (Accuracy and Precision); 3.3.1 Measurement Deviations; 3.3.2 Random Deviations - Influence on Precision; 3.3.3 Systematic Deviations - Influence on Accuracy; 3.3.4 Gross Errors; 3.3.5 Uncertainty of Measurement Results
- 3.3.6 Non-statistical Methods of Estimation3.3.7 Expressing Analytical Results; 3.3.8 Significant Figures - "Box-and-Dot" Method; 3.3.9 Outlier Tests; 3.4 Regression; 3.4.1 Regression Analysis; 3.4.2 Calibration Function; 3.4.3 The "Optimal" Trend Line; 3.4.4 Linear Regression; 4: The Analytical Process; 4.1 The Analytical Process in the Overall Context; 4.2 Planning Phase; 4.2.1 Analytical Problem; 4.2.2 Object of Investigation; 4.2.3 Sample; 4.2.4 Sampling; 4.2.5 Examination Procedures; 4.2.6 Analyte; 4.2.7 Literature and Database Research; 4.3 Analysis; 4.3.1 Measurement
- 4.3.2 Method Optimization4.3.3 Calibration; 4.4 Assessment; 4.4.1 Quantification; 4.4.2 ("True") Content; 4.5 Validation; 4.5.1 Validation Elements; 4.5.2 Using the Computer; 4.6 Final Documentation; 4.6.1 Review; 5: Example of a Validation Strategy; 5.1 Determination of Phenol in Industrial Waste Water; 5.1.1 Confirmation of Identity; 5.1.2 Sample Content Determination; 5.1.3 Selection; 6: Organizational and Practical Procedures in the Teaching Laboratory Program; 6.1 Goals; 6.2 Safety in the Laboratory Class; 6.3 Experimental Project Workflow; 6.3.1 Preparation; 6.3.2 Laboratory Notebook
- 6.4 ReportsReferences; 7: Literature; 7.1 Cited Literature; 7.2 Recommended Norms (Selection); 7.2.1Calibration; 7.2.2Inter-laboratory Tests; 7.2.3Quality Management; 7.3 Suggested Books (Selection); 8: Projects; 8.1 Chromatography; 8.1.1 Gas Chromatography - GC, Project: Tanker Accident; 8.1.1.1 Analytical Problem; 8.1.1.2 Introduction; 8.1.1.3 Material and Methods; 8.1.1.4 Questions; References; 8.1.2 Gas Chromatography Coupled with Mass Selective Detection - GC/MS, Project: "Circumvention of the Formerly Mandatory Declaration of Fragrances in Perfumes?"; 8.1.2.1 Analytical Problem
- 8.1.2.2 Introduction
