Metal-based neurodegeneration from molecular mechanisms to therapeutic strategies

Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiatric disturbances. Many of the key factors leading to neurodegenerative diseases are similar, including the dysfunction of metal ion homeosta...

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Bibliographic Details
Main Author: Crichton, Robert R. (-)
Other Authors: Ward, Roberta J.
Format: eBook
Language:Inglés
Published: Chichester, West Sussex, U.K. : Wiley 2014.
Edition:Second edition
Subjects:
See on Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009664725806719
Table of Contents:
  • Brain function, physiology, and the blood-brain barrier
  • Role of metal ions in brain function, metal transport, storage, and homeostasis
  • Immune system and neuroinflammation
  • Oxidative stress in neurodegenerative diseases
  • Aging and mild cognitive impairment, MCI
  • Parkinson's disease
  • Alzheimer's disease
  • Huntington's disease and polyglutamine expansion neurodegenerative diseases
  • Friedreich's ataxia and diseases associated with expansion of non-coding triplets
  • Creutzfeldt-Jakob and other prion diseases
  • Amyotropic lateral sclerosis
  • Alcoholic brain damage
  • Other neurological diseases
  • Therapeutic strategies to combat the onset and progression of neurological diseases.