Insulin-Like Growth Factors in Development, Cancers and Aging

This Special Issue of Cells on “Insulin-Like Growth Factors in Development, Cancers and Aging” provides a collection of modern articles dealing with the role of insulin-like growth factors (IGF1) in cancer biology, aging and development. Featured articles explore basic and clinical aspects of the IG...

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Bibliographic Details
Other Authors:	Werner, Haim (Editor)
Format:	eBook
Language:	Inglés
Published:	Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:	Research & information: general Biology, life sciences IGF-I IGF-II insulin IGF-IR IRs tyrosine kinase receptor GPCRs hybrids phosphorylation G-proteins β-arrestins functional RTK/GPCR hybrid nuclear translocation IGF-I receptor signaling targeted therapeutics IGF-Trap IGF system IGFBP-3 IGFBP-3R TMEM219 anti-tumor anti-metastatic agonists mAb therapy IGF-1 IGFBP-1 older adults longevity health-span age-related disease cognitive impairment diabetes mitochondria growth hormone insulin-like growth factor-1 aging oxidative stress senescence longitudinal study IGFBP mouse models skeletal muscle MSCs myogenesis glucose regulated protein (GRP) 94 insulin-like growth factor obligate chaperone hypertrophy atrophy cachexia muscle regeneration autophagy IGF-1R insulin receptor IR-A structural studies receptor activation
See on Biblioteca Universitat Ramon Llull:	https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009654981306719