Aneuploidy in health and disease

Aneuploidy means any karyotype that is not euploid, anything that stands outside the norm. Two particular characteristics make the research of aneuploidy challenging. First, it is often hard to distinguish what is a cause and what is a consequence. Secondly, aneuploidy is often associated with a per...

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Detalles Bibliográficos
Otros Autores: Storchova, Zuzana (Editor), Storchova, Zuzana, editor (editor)
Formato: Libro electrónico
Idioma:Inglés
Publicado: Rijeka, Croatia : IntechOpen 2012
[2012]
Materias:
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009654492306719
Descripción
Sumario:Aneuploidy means any karyotype that is not euploid, anything that stands outside the norm. Two particular characteristics make the research of aneuploidy challenging. First, it is often hard to distinguish what is a cause and what is a consequence. Secondly, aneuploidy is often associated with a persistent defect in maintenance of genome stability. Thus, working with aneuploid, unstable cells means analyzing an ever changing creature and capturing the features that persist. In the book Aneuploidy in Health and Disease we summarize the recent advances in understanding the causes and consequences of aneuploidy and its link to human pathologies.
Descripción Física:1 online resource (258 pages)
ISBN:9789535152965
Acceso:Open access