Molecular Mechanisms of Sensorineural Hearing Loss and Development of Inner Ear Therapeutics

The sense of hearing is vulnerable to environmental challenges, such as exposure to noise. More than 1.5 billion people experience some decline in hearing ability during their lifetime, of whom at least 430 million will be affected by disabling hearing loss. If not identified and addressed in a time...

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Detalles Bibliográficos
Otros Autores:	Vlajkovic, Srdjan M (Editor)
Formato:	Libro electrónico
Idioma:	Inglés
Publicado:	Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Materias:	Medicine brain-derived neurotrophic factor TrkB inner ear development zebrafish mitochondria dysfunction reactive oxygen species hypoxic d-galactose high-fat diet aging hearing loss astrocytes auditory brainstem lateral superior olive gap junctions voltage-activated calcium channel 1.3 otoferlin spontaneous activity deafness circadian dysregulation clock genes noise-induced hearing loss sensory hair cells synaptic ribbons sensorineural hearing loss hyperbaric oxygenation adjunctive therapy microRNAs cochlear nucleus inferior colliculus neuroplasticity noise-induced cochlear injury cochlear rescue otoprotection adenosine A1 receptor regulator of G protein signalling 4 CCG-4986 intratympanic drug delivery potassium voltage-gated channel subfamily q member 4 potassium nonsyndromic hearing loss KCNQ4 activator age-related hearing loss selegiline chronic oral treatment hearing protection mouse model
Ver en Biblioteca Universitat Ramon Llull:	https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009654466206719