The Patient Equation The Data-Driven Future of Precision Medicine and the Business of Health Care
How the data revolution is transforming biotech and healthcare--and why you can't afford to let it pass you byWe are living through a time when the digitization of health and medicine is becoming a reality, with new abilities to improve outcomes for patients as well as the efficiency and succes...
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| Formato: | Libro electrónico |
| Idioma: | Inglés |
| Publicado: |
Newark :
John Wiley & Sons, Incorporated
2020.
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| Materias: | |
| Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009644303706719 |
Tabla de Contenidos:
- Cover
- Title Page
- Copyright
- Contents
- Introduction
- PART 1 From Hippocrates to Epocrates
- Chapter 1 Before We Cured Scurvy
- Nanometers to Megameters
- Scurvy
- The False Promise of Genotype
- Your Very Own High‐frequency Medical Device
- Notes
- Chapter 2 Inside the Equations
- Like Lions of the Serengeti
- The Layer Cake
- Patients Like You, Patients Like Me
- Changing the Frequency
- Reverse‐engineering the Critical Layers
- The Cognitive Dimension
- Better Measurements at Virtually No Cost
- From Hypothesis Confirmation to Hypothesis Generation
- Notes
- Chapter 3 Fitbits, Smart Toilets, and a Bluetooth‐enabled Self‐driving ECG
- Are Apps the New Snake Oil?
- Wearables for Panicked Dogs
- It's the Equations, Not the Devices
- Let's Start with the Thermostat
- Notes
- PART 2 Applying Data to Disease
- Chapter 4 Ava-Tracking Fertility, on the Road Toward Understanding All of Women's Health
- Enter Ava
- The Changing Role of the Patient
- The Motivation to Comply
- A Man Who Just Can't Ovulate
- Finding a Niche in a Crowded Field
- Notes
- Chapter 5 One Breath, One Drop-Asthma and Diabetes, Chronic Conditions Being Conquered with Technology
- Out of the Danger Zone
- Lowering Barriers to Zero
- A Perfectly Artificial Pancreas
- Hacking One's Own Device
- One Drop at a Time
- Notes
- Chapter 6 Flumoji and Sepsis Watch-Two Approaches to Predicting and Preventing Acute, Life‐threatening Conditions Through Smarter Data
- Catching Sepsis Earlier
- Partnering with Doctors, Not Replacing Them
- Looking Beyond Sepsis
- Using Crowdsourcing to Track the Flu
- Stopping the Spread of Illness with Data Is Hard
- Notes
- Chapter 7 Cancer and Phage Therapy-Crafting Custom Treatments Just for You
- Changing the Way We Look at Cancer
- p53‐ologists of the Future.
- Or Perhaps Car‐t‐ographers of the Present
- Personalized Immunotherapy Beyond Cancer
- Notes
- Chapter 8 Castleman Disease-Not One RareDisease with NoTreatments, ButThree Rare Diseases. . . with Hope,Thanks to Data
- Finding Clusters in a Random World
- Dr. David Fajgenbaum's Quest for a Cure
- Rare Diseases, Common Problems
- Notes
- PART 3 Building Your Own Patient Equations
- Chapter 9 The Steam Table
- Progressing Toward Alzheimer's Disease...or Maybe Not
- When the Measurement and the Therapy Are One and the Same
- Steam Tables for Cancer
- The Data Problem
- From Wellness to Illness-and Back Again
- Notes
- Chapter 10 Good Data
- The Failure of Watson
- The Mars Climate Orbiter
- The Progression to Value
- Notes
- Chapter 11 Changing Clinical Trials
- Expanding Access to Trials
- Pharma's Lack of Connection to Clinical Care
- Truly Patient‐centric Trials
- Accepting New Kinds of Data
- Unshackling the Clinical Trial
- Enter Thomas Bayes
- Breaking the Barrier
- Synthetic Control Arms
- Our Synthetic Control Model
- Making Every Trial an Adaptive Trial
- A Stroke of Insight
- Notes
- Chapter 12 Disease Management Platforms
- The Promise of Mobile Apps
- Digital from the Beginning
- But It's Not That Easy
- Where That Leaves Us
- Notes
- PART 4 Scaling Progress to the World
- Chapter 13 The Importance of Collaboration
- A Tiny Island or a Larger Ecosystem
- How Data Collaboration Can Change the Game
- Notes
- Chapter 14 Value‐based Reimbursement
- Beyond Survival
- The (Mathematical) Fountain of Youth
- Money‐back Guarantee
- Making Value‐based Care the Future
- Notes
- Chapter 15 Aligning Incentives
- Human Doctors, Digital Doctors
- Respecting the Unquantifiable
- Empowered Patients
- Notes
- Chapter 16 And Then, a Pandemic
- Phase Diagrams Revisited.
- Steam Tables, Sensors, and Early Warning Systems
- Putting a Spotlight on the Fragility of Our System
- A Speedier Road to Modernized Trial Design
- The Next Hundred Years
- Notes
- Conclusion
- Acknowledgments
- About the Authors
- Index
- EULA.
