Computer-aided applications in pharmaceutical technology
Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experi...
| Other Authors: | , |
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| Format: | eBook |
| Language: | Inglés |
| Published: |
Cambridge, UK :
Woodhead Publishing
2013.
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| Edition: | 1st edition |
| Series: | Woodhead Publishing series in biomedicine,
no. 52 Woodhead Publishing series in biomedicine ; no. 52. |
| Subjects: | |
| See on Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009628627206719 |
Table of Contents:
- Cover; Computer-aided applications in pharmaceutical technology; Copyright; Contents; List of figures; List of tables; List of abbreviations; About the editor; About the contributing authors; Introduction; 1. Quality-by-design in pharmaceutical development; 1.1 Introduction; 1.2 ICH Q8 guideline; 1.3 Regulatory and industry views on QbD; 1.4 Scientifi cally based QbD - examples of application; 1.5 Conclusion; 1.6 Notes; 1.7 References; 2. Computeraided formulation development; 2.1 Introduction; 2.2 Application of computeraided techniques in development of pharmaceutical emulsions
- 2.3 Application of computeraided techniques in development of microemulsion drug carriers2.4 Conclusion; 2.5 References; 3. Experimental design application and interpretation in pharmaceutical technology; 3.1 Introduction; 3.2 Theory; 3.3 Examples; 3.4 References; 4. Chemometric methods application in pharmaceutical products and processes analysis and control; 4.1 Introduction; 4.2 Theory; 4.3 Examples; 4.4 References; 5. Neural computing in pharmaceutical products and process development; 5.1 Artificial neural networks; 5.2 Fuzzy logic; 5.3 Decision trees
- 5.4 Evolutionary computing and genetic algorithms5.5 Selforganizing maps; 5.6 Conclusion; 5.7 References; 6. Computeraided biopharmaceutical characterization: gastrointestinal absorption simulation; 6.1 Introduction; 6.2 Theoretical background; 6.3 Model construction; 6.4 Parameter sensitivity analysis; 6.5 Virtual trial; 6.6 Fed vs. fasted state; 6.7 In vitro dissolution and in vitro-in vivocorrelation; 6.8 Biowaiver considerations; 6.9 Conclusions; 6.10 References; 7. Computational fluid dynamics: applications in pharmaceutical technology; 7.1 Introduction; 7.2 Theoretical background
- 7.3 Application of CFD in pharmaceutical technology7.4 Conclusion; 7.5 References; Appendix; Index
