Methyl bromide risk characterization in California

Methyl bromide risk characterization in California

Detalles Bibliográficos
Autor Corporativo: National Research Council (U.S.) Subcommittee for the Review of the Risk Assessment of Methyl Bromide (-)
Formato: Libro electrónico
Idioma:Inglés
Publicado: Washington, D.C. : National Academy Press 2000.
Edición:1st ed
Colección:Compass series (Washington, D.C.)
Materias:
Bromomethane > Toxicology > California.
Health risk assessment > California.
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009622280606719
Tabla de Contenidos:
  • METHYL BROMIDE RISK CHARACTERIZATION IN CALIFORNIA
  • Copyright
  • Preface
  • Contents
  • Executive Summary
  • THE SUBCOMMITTEE'S TASK
  • THE SUBCOMMITTEE'S EVALUATION
  • Toxicology
  • Recommendations
  • Exposure
  • Recommendations
  • Risk Characterization
  • Recommendations
  • 1 Introduction
  • BACKGROUND
  • CALIFORNIA REGULATIONS
  • THE SUBCOMMITTEE'S TASK
  • ORGANIZATION OF THE REPORT
  • 2 Toxicology and Hazard Identification
  • PHARMACOKINETICS
  • GENOTOXICITY
  • ACUTE TOXICITY
  • SUBCHRONIC TOXICITY
  • CHRONIC INHALATION AND ONCOGENICITY
  • REPRODUCTIVE TOXICITY
  • DEVELOPMENTAL TOXICITY
  • NEUROTOXICITY
  • SELECTION OF CRITICAL EFFECTS FOR ACUTE TOXICITY
  • 3 Exposure Assessment
  • BACKGROUND
  • LIKELY EXPOSURE SCENARIOS
  • QUALITY OF DATA AVAILABLE FOR CHARACTERIZING EXPOSURES
  • Analytical Methods
  • Representativeness of Available Exposure Measurements
  • Appropriateness of Normalizing Assumptions for Different Application Rates
  • Appropriateness of Exposure-Duration Assumptions
  • ACCURACY AND APPROPRIATENESS OF AVAILABLE MODELING TOOLS
  • Exposure Estimates Based on Modeling
  • Exposure of Residents in a Fumigated House
  • Exposure of Residents Downwind from Soil Fumigations
  • SUMMARY
  • 4 Risk Characterization
  • RISK CHARACTERIZATION GOALS
  • HAZARD IDENTIFICATION
  • Acute Toxicity Database
  • Subchronic Toxicity Database
  • Chronic Toxicity Database
  • Developmental Neurotoxicity
  • EXPOSURE ASSESSMENT
  • Appropriateness of Acute-Exposure Definition
  • Subchronic Exposure
  • Chronic Exposure
  • MARGIN-OF-EXPOSURE ANALYSIS
  • Categories with More than Two Data Points
  • Categories with One or Two Data Points
  • UNCERTAINTY ISSUES
  • Derivation of Reference Concentrations
  • Sensitive Subpopulations
  • Multiple Exposures
  • SUMMARY
  • 5 Conclusions and Recommendations
  • TOXICOLOGICAL INFORMATION
  • Conclusions
  • Recommendations.
  • EXPOSURE ASSESSMENT
  • Conclusions
  • Recommendations
  • RISK CHARACTERIZATION
  • Conclusions
  • Recommendations
  • References
  • Appendix A Biographical Information on the Subcommittee for the Review of the Risk Assessment of Methyl Bromide
  • Appendix B Public Access Materials
  • Appendix C Calculation of Air Exchange Rates
  • ILLUSTRATIVE LOGNORMAL TREATMENT OF DATA FOR SELECTED OCCUPATIONAL EXPOSURES.

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