Use of laboratory animals in biomedical and behavioral research

Detalles Bibliográficos
Autores Corporativos: National Research Council (U.S.). Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research (-), Institute of Medicine (U.S.)
Formato: Libro electrónico
Idioma:Inglés
Publicado: Washington, D.C. : National Academy Press 1988.
Edición:1st ed
Materias:
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009622150506719
Tabla de Contenidos:
  • Use of Laboratory Animals in Biomedical and Behavioral Research
  • Copyright
  • Contents
  • Preface
  • Executive Summary
  • PATTERNS OF ANIMAL USE
  • BENEFITS DERIVED FROM THE USE OF ANIMALS
  • ALTERNATIVE METHODS IN BIOMEDICAL AND BEHAVIORAL RESEARCH
  • REGULATORY ISSUES
  • USE OF POUND ANIMALS
  • 1 Introduction
  • HISTORICAL BACKGROUND
  • Use of Animals in Research
  • Concerns Over Animal Use
  • PRESENT SITUATION
  • 2 Patterns of Animal Use
  • NUMBERS OF ANIMALS USED
  • USE OF ANIMALS IN RESEARCH BY THE FEDERAL GOVERNMENT
  • USE OF ANIMALS IN EDUCATION
  • USE OF ANIMALS IN TESTING
  • NEW TECHNOLOGIES AND FUTURE LABORATORY USE OF ANIMALS
  • SUMMARY
  • 3 Benefits Derived from the Use of Animals
  • POLIO
  • ACQUIRED IMMUNE DEFICIENCY SYNDROME
  • TRANSPLANTATION
  • CARDIOVASCULAR-RENAL SYSTEMS
  • NERVOUS SYSTEM
  • Movement and Function
  • Behavior
  • Postnatal Development of the Visual Cortex and the Influence of Environment
  • Memory
  • Pain
  • OTHER BENEFITS FOR HUMANS
  • BENEFITS FOR ANIMALS
  • SUMMARY
  • 4 Alternative Methods in Biomedical and Behavioral Research
  • RELATIONSHIPS AMONG LIFE FORMS
  • ANIMAL MODELS
  • ALTERNATIVES TO MAMMALS
  • Nonmammalian Vertebrates
  • Invertebrates
  • Microorganism
  • Cell and Tissue Cultures
  • Human Tissues
  • In Vitro Systems and Mathematical Models
  • Refinements
  • ALTERNATIVE METHODS IN TESTING
  • SUMMARY
  • 5 Regulatory Issues
  • APPROACHES TO REGULATION
  • FEDERAL REGULATIONS
  • Legislation Passed in 1985: The Health Research Extension Act and the Food Security Act
  • GOVERNMENT POLICY STATEMENTS
  • Guide for the Care and Use of Laboratory Animals
  • Public Health Service Policy on Humane Care and Use of Laboratory Animals
  • Good Laboratory Practices Regulations
  • STATE REGULATIONS
  • APPROACHES TO REGULATION
  • Granting Agency Approach to Regulation
  • Self-Regulation
  • EFFECTS OF REGULATIONS.
  • Effects on Training and Education
  • Effects on Experimental Results
  • Effects on Direct Expense of Research
  • Effects on the Animals
  • ENFORCEMENT AND ENACTMENT OF REGULATIONS AND LAWS
  • 6 Use of Pound Animals
  • SUPPLY OF POUND ANIMALS
  • REGULATIONS
  • SCIENTIFIC CONSIDERATIONS
  • BENEFITS
  • COST CONSIDERATIONS
  • CONCERNS FOR THE ANIMALS
  • 7 Conclusions and Recommendations
  • RECOMMENDATIONS
  • References
  • Individual Statements by Members of the Committee on the Use of Laboratory Animals in Biomedical and ...
  • ARTHUR C. GUYTON
  • CHRISTINE STEVENS
  • Appendix A 1896 Report of the National Academy of Sciences
  • Appendix B Curricula Vitae of Committee Members
  • Appendix C Invited Speakers at Committee Meetings
  • Index.