Dietary reference intakes : a risk assessment model for establishing upper intake levels for nutrients

Dietary reference intakes a risk assessment model for establishing upper intake levels for nutrients

Detalles Bibliográficos
Autor Corporativo: Institute of Medicine (U.S.). Food and Nutrition Board (-)
Formato: Libro electrónico
Idioma:Inglés
Publicado: Washington, D.C. : National Academy Press 1998.
Edición:1st ed
Colección:Compass series (Washington, D.C.)
Materias:
Diet.
Nutrition.
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009622046506719
Tabla de Contenidos:
  • Dietary Reference Intakes: A Risk Assessment Model for Establishing Upper Intake Levels for Nutrients
  • Copyright
  • Contents
  • Dietary Reference Intakes: A Risk Assessment Model for Establishing Upper Intake Levels for Nutrients
  • INTRODUCTION
  • WHAT ARE DIETARY REFERENCE INTAKES?
  • Recommended Dietary Allowance
  • Process for Setting the RDA
  • Adequate Intake
  • Tolerable Upper Intake Level
  • APPROACH FOR SETTING DIETARY REFERENCE INTAKES, INCLUDING TOLERABLE UPPER INTAKE LEVELS
  • Terminology
  • Concept
  • MODEL FOR THE DERIVATION OF TOLERABLE UPPER INTAKE LEVELS
  • RISK ASSESSMENT AND FOOD SAFETY
  • Basic Concepts
  • Steps in the Risk Assessment Process
  • Thresholds
  • APPLICATION OF THE RISK ASSESSMENT MODEL TO NUTRIENTS
  • Special Problems Associated with Substances Required for Human Nutrition
  • Consideration of Variability in Sensitivity
  • Bioavailability
  • Nutrient-Nutrient Interactions
  • Other Relevant Factors Affecting Bioavailability of Nutrients
  • STEPS IN THE DEVELOPMENT OF THE TOLERABLE UPPER INTAKE LEVEL
  • Step 1. Hazard Identification
  • Step 2. Dose-Response Assessment
  • Data Selection
  • Identification of NOAEL (or LOAEL) and Critical Endpoint
  • Uncertainty Assessment
  • Characterization of the Estimate and Special Considerations
  • DERIVATION OF ULS: SUMMARY OF PROGRESS TO DATE
  • Derivation of UFs
  • Derivation of a UL
  • Derivation of a UL for Other Groups
  • References
  • Appendix A Recommended Dietary Intakes for Individuals
  • Appendix B Options for Dealing with Uncertainties
  • References
  • Appendix C Reference Heights and Weights for Children and Adults
  • Appendix D Case Studies of Application of Risk Assessment Model for Nutrients
  • A. Calcium
  • Hazard Identification
  • Nephrolithiasis
  • Hypercalcemia and Renal Insufficiency (Milk-Alkali Syndrome)
  • Calcium/Mineral Interactions.
  • Dose-Response Assessment
  • Adults: Ages 19 through 70 Years
  • Infants: Ages 0 through 12 Months
  • Toddlers, Children, and Adolescents: Ages 1 through 18 years
  • Older Adults: Ages &gt
  • 70 Years
  • Pregnancy and Lactation
  • Special Considerations
  • Exposure Assessment
  • Risk Characterization
  • References
  • B. Folate
  • Hazard Identification
  • Adverse Effects
  • Summary
  • Dose-Response Assessment
  • Adults
  • Folate UL Summary, Adults
  • Other Life Stage Groups
  • Special Considerations
  • Intake Assessment
  • Risk Characterization
  • References
  • C. Riboflavin
  • Hazard Identification
  • Dose-Response Assessment
  • Special Considerations
  • Intake Assessment
  • Risk Characterization
  • References
  • Appendix E Biographical Sketches of Subcommittee on Upper Reference Levels of Nutrients
  • FNB Staff.

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