Regulation of tissue oxygenation
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere an...
| Autor principal: | |
|---|---|
| Formato: | Libro electrónico |
| Idioma: | Inglés |
| Publicado: |
San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) :
Morgan & Claypool
c2011.
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| Colección: | Colloquium digital library of life sciences.
Colloquium series on integrated systems physiology, from molecule to function, # 17. |
| Materias: | |
| Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009622022806719 |
Tabla de Contenidos:
- Introduction
- The circulatory system and oxygen transport
- Design of the cardiovascular system
- Hemodynamics
- Flow of blood through single vessels
- Structure and function of the microcirculation
- Transcapillary exchange of solutes
- Regulation of blood flow
- Local regulation of blood flow
- Mechanisms of local regulation
- Myogenic mechanism
- Metabolic mechanism
- Other oxygen-linked mechanisms of flow regulation
- Propagated vasomotor responses
- The respiratory system and oxygen transport
- Physical chemistry of respiratory gases
- Gas laws
- Properties of gases in liquids: Henry's law
- Forms in which gases are carried
- Oxygen transport
- Gas exchange and diffusion
- Overall gas exchange
- Diffusion
- Fick's law of diffusion
- Summary of diffusion properties
- Gas exchange limited by diffusion and perfusion
- Oxygen in the blood
- Blood: plasma and red blood cells
- Hemoglobin (heme + globin)
- Binding of oxygen to hemoglobin: oxygen saturation (dissociation) curve
- Allosteric effectors of oxygen binding to hemoglobin
- Overall oxygen transport
- Carboxyhemoglobin
- Artificial oxygen carriers
- Hemoglobin-based oxygen carriers
- Perfluorocarbon emulsions
- Chemical regulation of respiration
- Response to altered oxygen
- Central and peripheral respiratory chemoreceptors
- Tissue gas transport
- Utilization of oxygen by tissues
- Mitochondria
- Role of nitric oxide
- Role of myoglobin in striated muscle
- Oxygen transport in the microcirculation
- Longitudinal (axial) profile of oxygen in arterioles
- Longitudinal (axial) profile of oxygen in a capillary
- Tissue oxygen transport: Krogh cylinder model
- Oxygen transport in normal and pathological situations
- Defects and compensations
- Description of oxygen transport using Fick's principle
- Stagnant hypoxia (hypoperfusion)
- Hypoxic hypoxia
- Anemic hypoxia
- Histotoxic hypoxia
- Summary of hypoxic conditions and responses
- Matching oxygen supply to oxygen demand
- Fick's principle
- Convective vs diffusive oxygen transport
- Matching oxygen supply to oxygen demand: role of arterioles and capillaries
- Oxygen profile along a capillary: mass balance
- Heterogeneity of blood flow and oxygen delivery
- Exercise and hemorrhage
- Exercise
- Fick's principle in exercise
- Temporal phases of exercise
- Microvascular approach to oxygen transport during
- Muscle contraction
- Limited oxygen release from red blood cells, effect of transit time
- Hemorrhage
- Fick's principle in hemorrhage
- Compensatory mechanisms in hemorrhage
- Measurement of oxygen
- Oxygen tension (Po2)
- Polarographic electrodes
- Phosphorescence quenching microscopy
- Hemoglobin oxygen saturation (So2)
- Spectrophotometry of hemoglobin
- Resonance raman spectroscopy of hemoglobin
- Summary
- References
- Author biography.
