Animal models of cognitive impairment
The costs associated with a drug's clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans. Featuring contributions from distinguished researchers in the field of cognitive the...
| Otros Autores: | , |
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| Formato: | Libro electrónico |
| Idioma: | Inglés |
| Publicado: |
Boca Raton :
CRC/Taylor & Francis
2006.
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| Colección: | Frontiers in neuroscience (Boca Raton, Fla.)
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| Materias: | |
| Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009621447106719 |
Tabla de Contenidos:
- Front Cover; Preface; About the Editors; Contributors; Contents; List of Illustrations; 1. Introduction; 2. Muscarinic Receptor Antagonists in Rats; 3. Nicotinic Receptor Antagonists in Rats; 4. Involvement of the NMDA System in Learning and Memory; 5. Animal Models and the Cognitive Effects of Ethanol; 6. Animal Models of Cognitive Impairment Produced by Developmental Lead Exposure; 7. Developmental Behavioral Toxicity of Methylmercury: Consequences, Conditioning, and Cortex
- 8. Executive Function following Developmental Exposure to Polychlorinated Biphenyls (PCBs): What Animal Models Have Told Us9. Modeling Cognitive Deficits Associated with Parkinsonism in the Chronic-Low-Dose MPTP-Treated Monkey; 10. Cognitive Impairment in Transgenic Mouse Models of Amyloid Deposition; 11. Cholinergic Receptor Knockout Mice; 12. Assessments of Cognitive Deficits in Mutant Mice; 13. Cognitive Pharmacology in Aging Macaques; 14. Cognitive Impairment following Traumatic Brain Injury; 15. Cognitive Impairment Models Using Complementary Species
- 16. Cognition Models and Drug DiscoveryIndex
