Fundamentals of clinical research bridging medicine, statistics, and operations
The scope of clinical research is to evaluate the effect of a treatment on the evolution of a disease in the human species.The treatment can be pharmacological, surgical, psychological/behavioral or organizational/logistic. The disease, intended as an impairment of a state of well-being or a conditi...
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| Formato: | Libro electrónico |
| Idioma: | Inglés |
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Milano :
Springer
c2007.
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| Edición: | 1st ed. 2007. |
| Colección: | Statistics for biology and health.
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| Materias: | |
| Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009461057106719 |
Tabla de Contenidos:
- Viability of Biological Phenomena and Measurement Errors
- Distinctive Aspects of a Biomedical Study Observational and Experimental Studies
- Observational Studies
- Defining the Treatment Effect
- Probability, Inference and Decision Making
- The Choice of the Sample
- The Choice of Treatments
- Experimental Design: Fallacy of “Before-After” Comparisons in Uncontrolled Studies
- Experimental Design: the Randomized Blinded Study as an Instrument to Reduce Bias
- Experimental Designs
- Study Variants Applicable to More than One Type of Design: Equivalence Studies, Interim Analyses, Adaptive Plans and Repeated Measurements
- The Drug Development Process and the Phases of Clinical Research.
