Good Research Practice in Non-Clinical Pharmacology and Biomedicine

Good Research Practice in Non-Clinical Pharmacology and Biomedicine

This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

Detalles Bibliográficos
Otros Autores: Bespalov, Anton (Editor), Bespalov, Anton. editor (editor), Michel, Martin C. editor, Steckler, Thomas. editor
Formato: Libro electrónico
Idioma:Inglés
Publicado: Cham : Springer Nature 2020
2020.
Edición:1st ed. 2020.
Colección:Handbook of Experimental Pharmacology ; 257
Materias:
Pharmacology.
Neurosciences.
Cardiology.
Oncology  .
Pharmacology/Toxicology.
Oncology.
Pharmacology/Toxicology
Neurosciences
Cardiology
Oncology
Pharmacology
Neuroscience
Internal Medicine
reproducibility
study design
data analysis
data reporting
data integrity
quality management
open access
Cardiovascular medicine
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009437768706719
Tabla de Contenidos:
  • 1. Quality in Non-GxP Research Environment
  • 2. Guidelines & Initiatives for Good Research Practice
  • 3. Learning from principles of evidence-based medicine to optimize nonclinical research practices
  • 4. General Principles of Preclinical Study Design
  • 5. Resolving the tension between exploration and confirmation in preclinical biomedical research
  • 6. Blinding and Randomization
  • 7. Out of control? Managing baseline variability in experimental studies with control groups
  • 8. Quality of Research Tools
  • 9. Genetic background and sex: impact on generalizability of research findings in pharmacology studies
  • 10. Building robustness intro translational research
  • 11. Minimum information and quality standards for conducting, reporting, and organizing in vitro research
  • 12. Minimum Information in In Vivo Research
  • 13. A reckless guide to P-values: Local evidence, global errors
  • 14. Electronic Lab Notebooks and Experimental Design Assistants
  • 15. Data storage
  • 16. Design of meta-analysis studies
  • 17. Publishers’ responsibilities in promoting data quality and reproducibility
  • 18. Quality governance in biomedical research
  • 19. Good Research Practice – Lessons from Animal Care & Use
  • 20. Research collaborations and quality in research: foes or friends?
  • 21. Costs of implementing quality in research practice.

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