Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity

The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A bette...

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Bibliographic Details
Other Authors: Changjun Yin (auth), Andreas J.R. Habenicht, Pasquale Maffia, Sarajo Mohanta
Format: eBook
Language:Inglés
Published: Frontiers Media SA 2017
Series:Frontiers Research Topics
Subjects:
See on Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009436031906719
Description
Summary:The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A better comprehension of these powerhouses of disease immunity will likely facilitate development to unprecedented and specific therapies to fight chronic inflammatory diseases.
Physical Description:1 electronic resource (235 p.)