Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges

Tissue fibrosis may occur for unknown causes or be the consequence of many pathological conditions including chronic inflammatory or infectious diseases, autoimmune disorders, graft rejection, or malignancy. On the other hand, malignant tumors have been identified in fibrotic tissues decades ago, an...

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Bibliographic Details
Other Authors:	Gabazza, Esteban C. (auth)
Format:	eBook
Language:	Inglés
Published:	MDPI - Multidisciplinary Digital Publishing Institute 2019
Subjects:	bleomycin regeneration antitumor efficacy lung cancer SOX2 leiomyosarcoma lung cancer (LC) nanoparticles cytokines hepatocellular carcinoma metabolic reprogramming hepatic stellate cells angiogenesis transforming growth factor-? anaplastic lymphoma kinase idiopathic pulmonary fibrosis growth factor pathogenesis cancer-associated fibroblasts fibrosis lipopolysaccharide DHA lncRNA SREBP-1 YAP protein S non-small cell lung cancer (NSCLC) omega-3 fatty acid inflammation metastasis clinical symptoms miRNA smooth muscle tumor of uncertain malignant potential Wnt interstitial fluid pressure heterogeneity hepatocytes myometrium tumor necrosis factor ? tumor tumor microenvironment extracellular matrix TAZ carcinogenesis cystic formation pulmonary fibrosis HBV cytokine genetic instability diagnosis EMT crizotinib Hippo pathway GPR120 marker HCV non-alcoholic steatohepatitis pathology common pathways apoptosis type I collagen GPR40 acute lung injury uterine fibroid renal injury pathophysiology reactive oxygen species immunohistochemistry SMAD butylidenephthalide leiomyoma cirrhosis Erk1/2 targeted therapy TGF-? mechanotransduction therapy breast cancer hepatocellular carcinoma (HCC) hepatic stellate cells (HSCs) idiopathic pulmonary fibrosis (IPF) cancer-associated fibroblasts (CAFs) cancer signal pathway tumor stiffness
See on Biblioteca Universitat Ramon Llull:	https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009433812806719