Systems Analytics and Integration of Big Omics Data

A “genotype"" is essentially an organism's full hereditary information which is obtained from its parents. A ""phenotype"" is an organism's actual observed physical and behavioral properties. These may include traits such as morphology, size, height, eye color...

Full description

Bibliographic Details
Other Authors:	Hardiman, Gary (auth)
Format:	eBook
Language:	Inglés
Published:	MDPI - Multidisciplinary Digital Publishing Institute 2020
Subjects:	precision medicine informatics drug sensitivity chromatin modification cell lines biocuration neurodegeneration multivariate analysis artificial intelligence epigenetics missing data sequencing clinical data class imbalance integrative analytics algorithm development for network integration deep phenotype non-omics data feature selection Gene Ontology miRNA-gene expression networks omics data plot visualization Alzheimer's disease tissue classification epidemiological data proteomic analysis genotype RNA expression indirect effect multi-omics dementia multiomics integration data integration phenomics network topology analysis challenges transcriptome enrichment analysis regulatory genomics scalability heterogeneous data systemic lupus erythematosus database microtubule-associated protein tau disease variants genomics joint modeling distance correlation annotation phenotype direct effect curse of dimensionality gene-environment interactions logic forest machine learning KEGG pathways multivariate causal mediation amyloid-beta bioinformatics pipelines support vector machine pharmacogenomics candidate genes tissue-specific expressed genes cognitive impairment causal inference
See on Biblioteca Universitat Ramon Llull:	https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009431797506719