Molecular mechanisms regulating cytotoxic lymphocyte development and function and their associations to human diseases

Molecular mechanisms regulating cytotoxic lymphocyte development and function and their associations to human diseases

Cytotoxic lymphocytes, comprised of NK cells and cytotoxic T cells, play a pivotal role in immune defense. By directed release of perforin-containing lytic granules, NK and cytotoxic T cells can eradicate pathogen-infected, tumorigenic, and otherwise stressed cells. By the virtue of cytokine and che...

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Detalles Bibliográficos
Otros Autores: Konrad Krzewski (auth), Krzewski, Konrad editor (editor), Bryceson, Yenan editor
Formato: Libro electrónico
Idioma:Inglés
Publicado: France : Frontiers Media SA 2015
2015
Colección:Frontiers Research Topics
Materias:
Microbiology & Immunology
Biology
Health & Biological Sciences
secretory lysosomes
NK cells
hemophagocytic histiocytosis
immune therapy
granzyme
lytic granules
Cytotoxicity
anti-tumor response
Immunological Synapse
Perforin
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009428042606719

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