Histamine H4 receptor : a novel drug target for immunoregulation and inflammation

Histamine H4 receptor a novel drug target for immunoregulation and inflammation

H4 R is the newest member of the histamine receptor family, which was discovered about twelve years ago. It is considered a very promising drug target. The effort to improve the pharmacokinetic properties of the currently available H4 R ligands is reflected in a steadily growing number of scientific...

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Detalles Bibliográficos
Otros Autores: Stark, Holger, author (author)
Formato: Libro electrónico
Idioma:Inglés
Publicado: London, England : De Gruyter 2013
2013.
Edición:1st ed
Colección:Versita discipline : Chemistry, Life Sciences
Materias:
Histamine.
G protein coupled receptors, H4R ligands, Inflammation, Autoimmune Disorders, Pruritus, Asthma, Allergy, Cancer, Drug Development, Drug Target, Clinical Candidates, Biogenic Amin.
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009423250106719
Tabla de Contenidos:
  • Front matter
  • Contents
  • Preface
  • Chapter 1 The histamine H4 receptor story
  • Chapter 2 Histamine H4 Receptor Ligands
  • Chapter 3 Histamine Metabolism
  • Chapter 4 Histamine Receptors and Inflammatory Cells
  • Chapter 5 Histamine in Asthmatic and Fibrotic Lung Disorders
  • Chapter 6 Histamine in Atopic Disorders: Atopic Dermatitis and Pruritus
  • Chapter 7 Non-professional Histamine Producing Cells, Immune Responses and Autoimmunity
  • Chapter 8 Histamine in Cancer
  • Chapter 9 Non Receptor-mediated Histamine Actions
  • Chapter 10 Perspectives in H4R Research and Therapeutic Exploitation
  • List of Figures
  • List of Tables
  • Index

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