IL-1α Medicine Sartans Surgery acute myeloid leukemia aneurysm aneurysm clipping aneurysm rupture aneurysmal subarachnoid hemorrhage animal model blast crisis cerebral aneurysm corticospinal tract decellularization delayed cerebral vasospasm diffusion tensor imaging endothelial cell estrogen female growth hybrid operating room hyperleukocytosis inflammation intracranial aneurysm intracranial hemorrhage intraoperative digital subtraction angiography ischemic stroke macrophage posterior circulation aneurysm rabbits