50+ population Bangladesh C4 complement CHEK2 Cushing syndrome ETS FRAP Germany GnRH Hashimoto’s disease MALDI-MSI MEN Moreland NUTS-1 PM2.5 PURE PURE study Poland Public health & preventive medicine Rayleigh TBARS Ukraine WHOQOL-BREF questionnaire academic youth access to health care adenomyosis air pollution alcohol amino acids anaerobic threshold