CA-LBM model DTB crystallizer K-MER zeolite L-alanine L-serine PXRD TRPXRD Technology: general issues amine aryl glycerol ethers asparagine monohydrate aspect ratio biocatalysis catalyst cellulose chiral separation chirality continuous continuous crystallization crystal growth crystal habit crystal needles crystal shape crystal size measurement crystallization curcumin cyanoethylation of methanol dendritic growth deracemization dielectric property