anticancer cancer inflammation 1,2,3-triazole 1,3,4-oxadiazole 3,4'-bis-guanidino 3-amino-4'-guanidino 3-vinylazetidin-2-ones 5-fluorouracil 5-fluoruracil 7-deaza-4'-thioadenosine derivatives ?-lactam ADC (antibody-drug conjugate) BRAF Bcl-2 inhibitors CAR (chimeric antigen receptor) COX-1 inhibitor CYP17A1 Chemistry Combretastatin A-4 CovDock DNA fragmentation DSD EGFR ELISA H1299 HDAC inhibitors HER2 HL-60 HT-29 cells