Medicine Schwann cells U-shaped vessel UrSuppe stem cell culture medium Vertical-Wheel adipose stem cells adipose-derived stem cell advanced therapy medicinal products allogeneic cell therapy arthroscopy arthrotomy autologous therapy axonal regeneration bio-process bioprocess bioreactor blood platelets cell aggregate cell culture techniques cell growth cell seeding cell therapies computational fluid dynamics differentiation disease modeling drug screening electrospinning embryonic stem cells expansion fibrin nerve conduits