Biology, life sciences Research & information: general Split-Hopkinson pressure bar adverse hemodynamics aneurysm anisotropy aorta aortic valve biaxial mechanical characterization biaxial mechanical testing bileaflet mechanical heart valve biomarker biomechanics blood damage calcification cardiac valves cardiovascular imaging cirrus collagen crimp collagen fiber architecture collagen fiber reorientation computational fluid dynamics constitutive modeling constitutive models curvature early detection elastin elastin degradation enzyme fibrosis