AMD AREDS2-HOME study Delphi ForeseeHome AMD Monitoring System® Medicine STARS® Sorsby Sorsby's fundus dystrophy Vascular Endothelial Growth Factor (VEGF) aflibercept aflibercept monotherapy age-related macular degeneration age-related macular degeneration (AMD) angiogenesis anti-VEGF anti-VEGF treatment anti-vascular endothelial growth factor arterial hypertension bevacizumab brolucizumab cardiovascular risk factors cataract surgery choriocapillaris choroidal neovascularisation choroidal neovascularization clinical trials comparative therapies disease activity effectiveness emerging treatment