Weibull dissolution model Wood’s apparatus accelerated stability test amorphisation amorphous amorphous polymeric salt amorphous solid dispersion amorphous solid dispersions anticancer drugs ball milling bicaludamide bioavailability characterization ciprofloxacin classification continuous processing crystallization crystallization tendency dissolution dissolution enhancement dissolution rate enrofloxacin evaporation granulation hot melt extrusion interaction intrinsic dissolution rate manufacturing methods mesoporous milling