Coronary Artery Surgery Study Score Framingham PROCAM QRISK Research & information: general SCORE acute myocardial infarction atherosclerosis atherosclerosis prevention cardiovascular disease cardiovascular risk cardiovascular risk factors carotid intima-media complex carotid plaque cigarette smoking control-theoretic model coronary artery disease coronary computed tomography angiography degenerative aortic stenosis early detection familial hypercholesterolemia fibrin clot fibrinolysis genetic screening heart failure high-risk plaque intima media thickness intravascular imaging logistic growth major adverse cardiac and cerebral events