"solid-state biocatalysis" 2-ketoglutarate generation Agaricomycotina Aspergillus niger Basidiomycota E. coli FMO Fe(II)/2-ketoglutarate-dependent dioxygenase Glide docking Lactobacillus plantarum MISO library Pseudomonas putida MnB1 Talaromyces flavus Technology: general issues abiotic manganese oxides amine-reactive phenazine ethosulfate biogenic manganese oxides cell wall anchor cyanide hydratase direct electron transfer enzyme cascade flavin glucose oxidase glucose sensor glycemic level monitoring glycosylation sites homology modeling hyaluronic acid hydroxy amino acids in vitro synthesis