70-kDa heat shock proteins Gan-Lu-Yin IL-6 IL-8 Low reactive Level Laser Therapy (LLLT) MMP-1 MMP-2 Medicine Mfa1 Porphyromonas gingivalis TLR2 Toll-like receptors alveolar bone loss aspiration pneumonia azithromycin biological processes (BP) bleeding on probing carotid artery calcification chewing ability chronic periodontitis computed tomography diabetes diabetic retinopathy diagnosis differentially gene expression (DEGs) epidemiological index fasting blood sugar follow-up study gene ontology gingival crevicular fluid