Campylobacter consisus Crohn’s disease Cry protein crystals Csep1p GTL-16 cells H3O+ Haloalkane dehalogenase L-tryptophan MCR-1 MTT assay N-acetyl-D-glucosamine PCDA adsorption agarose balance between crystal bond energy and destructive surface energies barium carbonate biochemical aspects of the protein crystal nucleation biomedicine biomimetic crystallization biomimetic materials biomineralization biomorphs bioprecipitation bioremediation bond selection during protein crystallization calcein calcium carbonate chitosan circular dichroism classical and two-step crystal nucleation mechanisms