Chemical processes LNG Lurgi syngas MINLP Mathematical models Technology: general issues autoassociative neural network big data bio-jet diesel co-hydrotreating coproduction cryogenic separation curricula design distribution energy systems engineering fuzzy optimization generalized disjunctive programming higher education hydrodeoxigenation hydrodesulphurisation input-output model integration mathematical programming methanol synthesis mixed-integer programming nonlinear principal component analysis nonlinear programming oil supply chain optimization