Fisher information matrix History of engineering & technology Jones polynomial Khovanov homology Monte-Carlo simulation Noether-like operator alpha-power skew-t distribution asymmetry barycentric coordinate system braid link compartment fire composite method computational efficiency confidence intervals conservation laws constrained optimization coordinate system derivative-free method derivative-free methods drone deployment drone port equal volume projection equivariant bifurcation theory extreme values facility location problem fast algorithms fixed points fractals full-scale fire experiment generalized Lane–Emden systems