Cladobotryum protrusum DNA methylation GRCh38 Gloeostereum incarnatum PacBio PacBio single molecule real-time sequencing SMRT sequencing Swedish population Tricoplusia ni allele-specific analysis bone marrow cell subpopulations cobweb disease cytochrome P450 enzyme (CYP) de novo assembly de novo genome assembly full length RNAseq gene expression human reference genome human whole-genome sequencing insect genome long-read SMRT sequencing low-input DNA mRNA isoforms mosquito mycoparasite next generation sequencing optical mapping population sequencing protein isoforms secondary metabolite